Investigating the Neuroprotective Effects of Flavonoids on Oxidative Stress, Tau Pathology, and Beta Amyloid Aggregation in Alzheimer’s Disease: A Systematic Literature Review
Faculty Mentor
Kenza Benzeroual
Major/Area of Research
Pharmacy/Complementary Alternative Medicine
Description
INTRODUCTION: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that is prevalent among older adults, characterized by cognitive decline, memory loss, and behavioral changes.
RESULTS: Although the pathological mechanisms of AD remain complex and unclear, key features include extracellular neuritic plaques composed of amyloid beta peptides and intracellular neurofibrillary tangles that contain hyper-phosphorylated tau proteins- which play a significant role in causing neuronal dysfunction.
CONCLUSION: Current treatments provide limited symptomatic relief without halting the progression of this disease.
Investigating the Neuroprotective Effects of Flavonoids on Oxidative Stress, Tau Pathology, and Beta Amyloid Aggregation in Alzheimer’s Disease: A Systematic Literature Review
INTRODUCTION: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that is prevalent among older adults, characterized by cognitive decline, memory loss, and behavioral changes.
RESULTS: Although the pathological mechanisms of AD remain complex and unclear, key features include extracellular neuritic plaques composed of amyloid beta peptides and intracellular neurofibrillary tangles that contain hyper-phosphorylated tau proteins- which play a significant role in causing neuronal dysfunction.
CONCLUSION: Current treatments provide limited symptomatic relief without halting the progression of this disease.